<p class="title">It was a tough day for seeded players at the BNP Paribas Open, with Novak Djokovic and Naomi Osaka, the world's top-ranked players, ushered out in the desert.</p>.<p class="bodytext">Djokovic and Philipp Kohlschreiber resumed their third-round match that was suspended because of rain a night earlier. The unseeded German knocked off the five-time tournament champion 6-4, 6-4.</p>.<p class="bodytext">Osaka lost to Belinda Bencic 6-3, 6-1 in just over an hour in the fourth round of the first title defence of her career.</p>.<p class="bodytext">"She sort of came out there really aggressive," Osaka said. "She sort of knew what she wanted to do more than me."</p>.<p class="bodytext">Since Osaka won the title at Indian Wells a year ago, she won the US and Australian Opens. Her triumph in Australia made her No. 1 for the first time, but her time at the top has been rocky. Osaka fired her coach and lost in the first round in Dubai before taking on a new coach, Jermaine Jenkins, who came on court during the match.</p>.<p class="bodytext">On Tuesday, the 23rd-ranked Bencic served and returned better.</p>.<p class="bodytext">The bottom half of the men's draw still includes No 2 seed Rafael Nadal and fourth-seeded Roger Federer, both of whom breezed to victory.</p>.<p class="bodytext">Djokovic owned an 8-1 record against Kohlschreiber, who beat a No 1 player for the first time.</p>.<p class="bodytext">Kohlschreiber liked the weather — sunshine and temperatures in the low 70s — much better than the cold and rain on Tuesday night.</p>.<p class="bodytext">"I liked my chances more at night against Kohlschreiber, but it wasn't to be last night," Djokovic said. "Completely different conditions today. I congratulate him for playing tactically really well and getting me out of my comfort zone. He deserved to win."</p>.<p class="bodytext">The 35-year-old German started thinking he had a chance early in the first set when he survived a handful of break points on his serve.</p>.<p class="bodytext">"I would say after 3-all in the first set I felt like getting closer to the set, holding my service games, which is not easy against Novak, because he's such a great returner," Kohlschreiber said. </p>.<p class="bodytext">Djokovic was just 1-for-5 on break-point opportunities. Kohlschreiber converted three of his four chances.</p>.<p class="bodytext">Next up for Kohlschreiber is Gael Monfils, who owns a 13-2 record against the German.</p>.<p class="bodytext">Djokovic remains alive in doubles with partner Fabio Fognini. Djokovic returned about an hour after his loss for their match.</p>.<p class="bodytext">Also ousted were No 6 Kei Nishikori, No. 10 Marin Cilic and No. 14 Daniil Medvedev.</p>.<p class="bodytext">Nadal eased by 25th-seeded Diego Schwartzman 6-3, 6-1, while Federer defeated Swiss countryman Stan Wawrinka 6-3, 6-4.</p>.<p class="bodytext">In women's fourth-round matches, No. 2 Simona Halep lost to Marketa Vondrousova 6-2, 3-6, 6-2 and No. 7 Kiki Bertens was beaten by 20th-seeded Garbine Muguruza 5-7, 6-1, 6-4.</p>.<p class="bodytext">Venus Williams reached the quarterfinals with a 6-4, 6-4 win over Mona Barthel.</p>.<p class="bodytext">Bianca Andreescu, an 18-year-old Canadian, beat 18th-seeded Wang Qiang 7-5, 6-2.</p>
<p class="title">It was a tough day for seeded players at the BNP Paribas Open, with Novak Djokovic and Naomi Osaka, the world's top-ranked players, ushered out in the desert.</p>.<p class="bodytext">Djokovic and Philipp Kohlschreiber resumed their third-round match that was suspended because of rain a night earlier. The unseeded German knocked off the five-time tournament champion 6-4, 6-4.</p>.<p class="bodytext">Osaka lost to Belinda Bencic 6-3, 6-1 in just over an hour in the fourth round of the first title defence of her career.</p>.<p class="bodytext">"She sort of came out there really aggressive," Osaka said. "She sort of knew what she wanted to do more than me."</p>.<p class="bodytext">Since Osaka won the title at Indian Wells a year ago, she won the US and Australian Opens. Her triumph in Australia made her No. 1 for the first time, but her time at the top has been rocky. Osaka fired her coach and lost in the first round in Dubai before taking on a new coach, Jermaine Jenkins, who came on court during the match.</p>.<p class="bodytext">On Tuesday, the 23rd-ranked Bencic served and returned better.</p>.<p class="bodytext">The bottom half of the men's draw still includes No 2 seed Rafael Nadal and fourth-seeded Roger Federer, both of whom breezed to victory.</p>.<p class="bodytext">Djokovic owned an 8-1 record against Kohlschreiber, who beat a No 1 player for the first time.</p>.<p class="bodytext">Kohlschreiber liked the weather — sunshine and temperatures in the low 70s — much better than the cold and rain on Tuesday night.</p>.<p class="bodytext">"I liked my chances more at night against Kohlschreiber, but it wasn't to be last night," Djokovic said. "Completely different conditions today. I congratulate him for playing tactically really well and getting me out of my comfort zone. He deserved to win."</p>.<p class="bodytext">The 35-year-old German started thinking he had a chance early in the first set when he survived a handful of break points on his serve.</p>.<p class="bodytext">"I would say after 3-all in the first set I felt like getting closer to the set, holding my service games, which is not easy against Novak, because he's such a great returner," Kohlschreiber said. </p>.<p class="bodytext">Djokovic was just 1-for-5 on break-point opportunities. Kohlschreiber converted three of his four chances.</p>.<p class="bodytext">Next up for Kohlschreiber is Gael Monfils, who owns a 13-2 record against the German.</p>.<p class="bodytext">Djokovic remains alive in doubles with partner Fabio Fognini. Djokovic returned about an hour after his loss for their match.</p>.<p class="bodytext">Also ousted were No 6 Kei Nishikori, No. 10 Marin Cilic and No. 14 Daniil Medvedev.</p>.<p class="bodytext">Nadal eased by 25th-seeded Diego Schwartzman 6-3, 6-1, while Federer defeated Swiss countryman Stan Wawrinka 6-3, 6-4.</p>.<p class="bodytext">In women's fourth-round matches, No. 2 Simona Halep lost to Marketa Vondrousova 6-2, 3-6, 6-2 and No. 7 Kiki Bertens was beaten by 20th-seeded Garbine Muguruza 5-7, 6-1, 6-4.</p>.<p class="bodytext">Venus Williams reached the quarterfinals with a 6-4, 6-4 win over Mona Barthel.</p>.<p class="bodytext">Bianca Andreescu, an 18-year-old Canadian, beat 18th-seeded Wang Qiang 7-5, 6-2.</p>