Pfizer is developing an oral weight loss drug called danuglipron, which belongs to a class of drugs called GLP-1 agonists. These drugs mimic a hormone that reduces appetite and increases satiety. Pfizer's drug is designed to be taken twice a day, without the need for fasting or injections. Danuglipron has shown promising results in a phase 2 clinical trial involving 411 adults with type 2 diabetes and obesity. The trial compared two doses of danuglipron (80 mg and 120 mg) with a placebo for 16 weeks. The results showed that danuglipron led to a statistically significant weight loss compared to placebo. The 120 mg dose resulted in an average weight loss of 10 pounds, while the 80 mg dose resulted in an average weight loss of 8.6 pounds. The placebo group lost only 2.2 pounds on average.
The weight loss achieved by danuglipron was similar to that of Ozempic, a GLP-1 agonist injection made by Novo Nordisk. Ozempic is approved for treating type 2 diabetes and is also used off-label for weight loss. A phase 3 trial of Ozempic showed that a 1 mg dose resulted in an average weight loss of 9.9 pounds over 30 weeks. However, Ozempic requires a weekly injection, which may be less convenient and more costly than an oral pill.
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*This celebrity does not endorse this product. This product is medically approved. These are some famous products of the market.
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However, danuglipron also had some drawbacks and challenges. The most common side effects were nausea, vomiting, and diarrhea, which affected up to 73%, 47%, and 25% of the participants, respectively. These side effects were mostly mild, but they led to more than half of the participants dropping out of the trial. Pfizer announced on Dec. 1 that it was discontinuing the phase 3 trial of the twice-daily version of danuglipron due to the high rates of adverse events. The company said it would focus on developing a once-daily version of the drug, which may have fewer side effects. Danuglipron is still in the early stages of development and it may take years before it gets approved and becomes available on the market. It is not clear how it will compare to other weight loss drugs, such as Wegovy, another GLP-1 agonist injection that is approved for chronic weight management and can cause more weight loss than Ozempic. Danuglipron may offer an advantage as an oral option, but it may also face competition from other oral GLP-1 agonists, such as Rybelsus, which is approved for type 2 diabetes and is being tested for weight loss² .
Danuglipron is a potential oral weight loss drug that may be as effective as Ozempic, but it also has some challenges and limitations. It may provide a more convenient and user-friendly alternative to injections, but it may also cause more side effects and dropouts. It may need further studies and trials to determine its safety, efficacy, and marketability.
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If you want to use OTC or prescription diet pills, you should talk to your doctor first. They can tell you the benefits and risks of each option, and they have to give you a prescription for the second one.
But how do you know when you need to ask your doctor about prescription diet pills? Here are some signs that might help you decide:
● Try to eat healthy food and exercise regularly. If you do this by yourself and it doesn’t work, you might need some advice from a fitness coach or a nutritionist.
● You can also try some natural diet pills that you can buy without a prescription. We have some examples of popular ones below. They might help you burn fat.
● Be patient and give yourself some time to see the results. Losing weight is not easy and it takes time. Usually, you need at least a month or two to notice any changes.
● But if you are very overweight, have trouble losing belly fat, and have tried everything else, then you might need to talk to your doctor about prescription diet pills.
Some Common Questions About OTC and Prescription Diet Pills Are Prescription Diet Pills Better Than OTC Ones? Prescription diet pills are usually stronger than OTC ones. They can help you lose weight faster, but they also have more side effects and risks. That’s why you need a doctor’s approval to use them.
But that doesn’t mean that prescription diet pills are always better than OTC ones. Some OTC diet pills are very effective and can compete with any prescription ones. You can see some of them in the list below.
Are Prescription Diet Pills Safe? Prescription diet pills are not completely safe. They can cause problems or complications, especially if you have other health issues. That’s why you need to follow your doctor’s instructions and check-ups when you use them.
What Is The Best Prescription Diet Pill? The best prescription diet pill depends on your situation. Your health, your weight, and your reasons for gaining weight can affect how diet pills work for you.
But one of the best options for most people is Qsymia. It is a combination of two drugs that can help you lose belly fat and control your hunger. It can make it easier for you to stick to your diet.
But you should know that Qsymia is not for long-term use and it can have serious side effects. So you should always talk to your doctor before you use it."
"How to Find the Best OTC Diet Pills? The best OTC diet pills for most people are Instant Knockout Cut. They are powerful pills that can burn fat, give you more energy, and make you less hungry. These pills can help you lose weight, keep your muscles, and improve your health in many ways.
Can You Get Prescription Diet Pills With Your Insurance? It depends on your insurance and your situation.
Some insurance companies do not pay for diet pills at all. Others will pay for them if a doctor says you need them.
If you want to get diet pills with your insurance, check your policy first. See what it covers and what it does not. If you talk to a doctor and they find a problem, your insurance might not cover it if you need to change your policy.
"Top 5 Weight Loss Pills in 2024: How to Lose Weight Fast and Easy with These Powerful Products
We have checked more than 24 of the best weight loss products that you can buy to see which ones can help you get rid of the extra pounds. We looked at each product based on what it has, what it does, how much it costs, how much you need to take, what people say about it, and what promises it makes.
There are many weight loss products that you can choose from. You can find fat burners, hunger blockers, metabolism enhancers, and diet pills that you can get without a prescription. But finding the right product can be very hard.
But don’t worry, we are here to help!
We have checked more than 24 of the best weight loss products that you can buy to see which ones can help you get rid of the extra pounds. We looked at each product based on what it has, what it does, how much it costs, how much you need to take, what people say about it, and what promises it makes.
If you want to lose weight, get rid of body fat, or you just want to look your best, here are the best weight loss pills that you can buy.
Best 5 Weight Loss Products of 2024
PhenQ: Best Product for Losing Weight Fast
PhenGold: Best Product for Making Your Metabolism Faster
TrimTone: Best Product for Stopping Your Hunger
Phen24: Best Product for Women Who Want to Lose Weight
PrimeShred: Best Product for Men Who Want to Lose Weight
#1) PhenQ: Best Weight Loss Product for Losing More Than 30 Pounds
PhenQ is the best weight loss product for men or women who need to lose more than 30 pounds. Most weight loss products have only one way to help you lose weight. PhenQ is different because it has many ways to help you lose weight. The complete formula has helped 190,000 people get the body they wanted.
The PhenQ fat burner product uses four different ways to help people lose weight:
Stopping your hunger
Making you feel more energetic
Stopping your body from making more fat
Burning the fat in your body
The fact that it also makes you feel happier is a nice extra.
PhenQ works for anyone who wants to lose a lot of weight. Even someone who wants to lose more than 30 pounds can use this new product. The amazing effects have made PhenQ one of the most trusted weight loss products that you can buy.
Each product has a-Lacys Reset, a thing that can lower fat and body weight while making your muscles stronger. Tests show that a-Lacys Reset helps people lose 7.24% of body fat and 3.44% of body weight. That’s on top of a 3.80% increase in muscle mass.
Other things in the PhenQ formula are:
Capsimax powder
Calcium carbonate
Caffeine without water
Chromium picolinate
L-carnitine fumarate
Nopal
Each bottle of PhenQ has 60 products, enough for one month. The maker says to take two products per day, one in the morning and one in the evening. Anyone who doesn’t see results can send back their PhenQ, no questions asked.
The PhenQ fat burner comes with free shipping and a 60-day money-back promise. People do not need a doctor’s note to buy PhenQ and can save money when they buy more than one. If you have any questions or comments, you can talk to PhenQ’s customer service anytime, any day.
#2) PhenGold: Best Product for Making Your Metabolism Faster PhenGold is the best fat burner product for making your metabolism faster. Your metabolism is very important for controlling your weight. Anyone who wants to burn more fat would benefit from a boost in their metabolism. PhenGold gives you exactly that in a weight loss product.
PhenGold uses strong ingredients that naturally make your metabolism faster. For example, scientific studies show that L-theanine helps you lose fat, while cayenne pepper makes you burn more calories every day. Other ingredients in PhenGold are:
Green tea extract
L-theanine
Rhodiola SP
Green coffee
L-tyrosine
Cayenne powder
PhenGold has many benefits for people who care about their health. The weight loss product does not have lactose, soy, or artificial ingredients. It also works for anyone who follows a vegetarian or vegan diet.
Each PhenGold bottle has 90 products. Take three products per day, with equal time between them. These weight loss products have only natural ingredients and have very few side effects.
The maker, Swiss Research Labs Ltd., makes all PhenGold in the United States. It also gives a 100% money-back promise and 24-hour delivery. You can save money on their products by buying more than a 1-month supply.
Powerful Fat Burner Product That Works For Both Men and Women
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"#4) Phen24: Best Weight Loss Product for Women Phen24 is our best choice for the best weight loss product for women. This product’s new formula gives the energy women need to look and feel their best. It has ingredients that make your metabolism faster and put your body in a state of thermogenesis.
The secret ingredient is glucomannan, a dietary fiber that dissolves in water and comes from konjac root. Each weight loss product has 1000 mg of glucomannan, an amount that is best according to scientific research in the European Union. The substance makes women feel full between meals so that they don’t eat too much.
The product has a daytime and nighttime formula that gives 24-hour fat burning support.
Phen24 Daytime products have the following ingredients:
● Copper
● Manganese
● Zinc
● Caffeine
● Iodine
● Cayenne Powder
● L-Phenylalanine
● Guarana Extract
● In the same way, the Phen24 Nighttime formula has:
● Chromium
● Calcium D-Pantothenate
● Pyridoxine Hcl
● Molybdenum
● Thiamine Hcl
● Griffonia Extract
● Green Tea Extract
● Choline Bilartrate
● Hops Extract
● D-Biotin
● Glucomannan
Phen24 does more than help women lose weight. The pill that gives energy can lower tiredness and fatigue, letting people handle the busiest social and professional schedules. The unique formula can even make concentration better.
Wolfson Brands Ltd., the company that makes Phen24, says to take one dose of daytime product per day before breakfast, then two products from nighttime bottle before evening meal, all with a glass of water. Taking the products at different times gives the best results, thanks to the non-stop fat-burning effect.
Phen24 gives a weight loss solution made for women. The formula that is tested by science doesn’t have strong stimulants or side effects that come with male weight loss products. A daily dose of Phen24 can help women get that stronger, slimmer body in no time.
"One of the Best Fat Burners For Women
Has Glucomannan, A Hunger Blocker That Works According to Science
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Natural Ingredients Found In Weight Loss Products That Work
● Green Tea Extract
Green tea is not only a good drink but a helpful weight loss product. Scientists have linked green tea extract to better hunger control and fat burning. The lots of caffeine also give the energy you’ll need to do hard workouts.
Weight loss products with green tea extract destroy fat cells before moving them into the blood. Green tea extract is an active thing for fat-burning hormones in the body, such as norepinephrine. The product also has antioxidants that stop the breakdown of norepinephrine, making it easier to get rid of fat.
● Green Coffee Bean Extract
A daily product of green coffee bean extract might be what you need to get the body you want. Coffee beans have a thing called chlorogenic acid that scientists think can stop aging, lower blood pressure, and burn fat. Note that making coffee beans hot may lower the amount of chlorogenic acid.
Green coffee benefits from the caffeine, which acts as a hunger blocker. The thing works with your nervous system to stop hunger signals from the stomach to the brain. Caffeine also starts thermogenesis, making the body produce heat and get energy from food.
● Garcinia Cambogia Extract
Garcinia cambogia extract comes from the Malabar tamarind and has become a more popular product. Scientists say that fruit extract stops the body from making fat and stops hunger. Garcinia cambogia can even control cholesterol and blood sugar levels.
Garcinia cambogia extract can burn fat cells, thanks to the hydroxycitric acid. The active thing stops the enzyme citrate lyase from making new fat. Hydroxycitric acid makes serotonin levels higher, meaning that one product of garcinia cambogia acts as a hunger blocker and mood maker.
● Bitter Orange
Bitter orange (Citrus aurantium) has a long history of medical uses in China and Brazil. According to Andrew Weil, M.D., native people in the Amazon use bitter orange to treat hard stools, feeling sick, and bad bowel movements. The sour fruit makes a thermogenic reaction linked to weight loss.
However, bitter orange is still a risky product and may cause bad side effects. The fruit has ephedra (ma-huang), a thing the U.S. Food and Drug Administration (FDA) stopped in 2014. The National Center for Complementary and Alternative Medicine has linked ephedra to higher blood pressure, heart attacks, and strokes. While natural ingredients are often safer than fake ones, bitter orange shows that that’s not always true.
● Chromium Picolinate
Chromium is a mineral that may make your fat metabolism faster and help you burn calories faster. The safe and natural thing comes in different forms, with food experts thinking trivalent chromium a needed part of a good diet. Weight loss product makers use it in products because of its effects on insulin.
Many studies show that chromium can make blood sugar levels better for people with sugar. It also has a chance as a weight-loss product. A four-month study found that people who got a daily product of the mineral lost 2.4 pounds more than those in the other group.
"- Raspberry Ketones
Raspberry ketone is a chemical that makes red raspberries smell good. You can also find it in other fruits and berries, and in some beauty products. Raspberry ketones have a similar shape to capsaicin and synephrine, which are chemicals that affect how your body burns fat.
Some scientists think that raspberry ketones can help your body burn fat faster. They have tested this idea on animals and found that it can increase metabolism and the release of adiponectin, which controls blood sugar levels. Raspberry ketones could be helpful for people with diabetes and people who want to lose weight.
● L-Carnitine
L-carnitine is an amino acid that helps with weight loss. It moves fatty acids into the mitochondria, where the cell uses a lot of fat for energy. You can get this amino acid from meat, fish, avocados, and beans.
Your body can make L-Carnitine, as well as other types of carnitine. For example, Acetyl L-Carnitine affects brain function, while Propionyl L-Carnitine improves blood flow. Some sports drinks have L-carnitine L-tartrate, which helps the body absorb minerals and recover from exercise.
● Caffeine
Caffeine is one of the stimulants that can make your metabolism faster, along with chlorogenic acid, theophylline, and theobromine. It is also the most common psychoactive substance in the world, and many people use it for weight loss pills. Caffeine can help you lose weight because it stops adenosine.
When adenosine is blocked, other brain cells can work, releasing chemicals like norepinephrine and dopamine. These chemicals make you feel alert and energetic. Caffeine also makes your metabolic rate higher, which means you can lose weight more easily over time. Some of the possible side effects of caffeine are a faster heart rate, nervousness, and trouble sleeping. Caffeine is a usual ingredient in many fat burners because it helps your body use more calories.
● Conjugated Linoleic Acid
Conjugated linoleic acid (CLA) is a fatty acid that you can find in dairy and meat products. Cows, goats, and other animals change omega-6 fatty acids from their food into CLA when they digest it. Researchers think that this substance helps with weight loss in humans.
One experiment gave mice conjugated linoleic acid for six weeks. The mice that ate CLA lost 70% more fat than the mice that did not. Another experiment on pigs found that CLA reduced body fat.
"The Top 5 Diet Supplements That Really Work
People have different ways of losing weight and gaining muscle. So we made this guide to show you the 5 best diet supplements that you can buy today. These supplements can help you get rid of extra fat and reach your weight loss goals.
Many people want to lose weight quickly and look for strong diet pills. Sometimes they ask for prescription pills that can melt fat fast. But these pills can have bad effects on your health. And you can find over-the-counter pills that work just as well and are safer.
But how do you choose the best diet pill for you? There are many kinds of diet supplements that do different things. They have different ingredients, amounts, and makers. It can be hard to decide which one to buy.
That’s why we made this guide to help you. We will show you the 5 best diet supplements that you can buy today. These supplements can help you get rid of extra fat and reach your weight loss goals.
Our Top Choices for Best Diet Supplements Best Diet Supplements Overall - Instant Knockout Cut
Best Diet Supplements for Women - Hourglass Fit
Best High-Quality Diet Supplements - Hunter Burn"
"Instant Knockout Cut - The Top Diet Supplement Overall
Instant Knockout Cut is a very popular diet supplement that many people use today. It was made to help fighters like boxers and MMA fighters lose weight the right way before a fight, without using anything that is not allowed by sports rules.
It does this by burning fat and keeping muscle. Many other diet pills can do this, but Instant Knockout Cut also has ingredients that make you less hungry and more energetic, so you can eat well and exercise more, and lose weight faster.
Instant Knockout Cut diet pills have only good and tested ingredients. They have glucomannan, green tea extract, black pepper extract, caffeine, cayenne pepper, l-theanine, and vitamins b6, b12, and d3. They are all in the right amount, so they work well and don’t cause problems.
Glucomannan is a kind of fibre that does not dissolve in water and is very good at making you feel full. It has very few calories, so it does not make you gain weight, and it works by soaking up water in your stomach, which makes it bigger and fills you up, so you can eat less and stay healthy (1).
It also helps your digestion and how your body uses nutrients, so everything works well and you don’t gain weight or make new fat cells.
Green tea extract also makes you feel full, but it is used in diet pills mostly because it has natural caffeine and a substance called catechin EGCG. These give you more energy and stop swelling, pain, and the gas that fibre can cause (2).
Caffeine is a strong substance that makes you more alert and heats up your body. This makes your body work faster and release hormones that burn fat, while giving you more energy to do harder workouts, and lose weight as fast as you can (3).
The substance l-theanine is often put in diet supplements that have caffeine, because it can stop you from feeling tired or having trouble sleeping. It can also make you less tired and heal faster, so you can exercise more and lose more weight and fat (4).
Cayenne pepper extract has a substance called capsaicin, and black pepper extract has a substance called piperine. Both of these make your body hotter and burn fat.
But they are mostly in diet pills because they also make other ingredients work better. They make your body absorb and use all the other ingredients in diet supplements faster and better, so they are more effective (5)(6).
The diet pills also have three vitamins, b6, b12, and d3. They help burn fat, control hunger, and make the other ingredients in the diet pills work better, while also keeping your heart and body healthy and strong while you lose weight (7)(8)(9).
By putting together the effects of ingredients that make you less hungry, more energetic, and burn fat in one diet pill, and also stopping any problems that some of the ingredients could cause, Instant Knockout Cut can help you lose weight in many ways.
It also has a good price, so Instant Knockout Cut is an easy choice to say it is the best diet pill for most people today.
"How to Make Diet Supplements Work Better for You Top weight loss pills are based on scientific studies and tests that have checked the drug’s quality before selling it. If you want to get the best body results, start by following the directions on the bottle. Doing what the maker says will lower the risk of bad side effects.
Diet pills are not the only thing that matters. You won’t get the perfect body if you don’t work out often or eat well. Add hard physical activity and healthy foods to your daily routine to get the results you want.
Kinds of Weight Loss Pills
● Fat Burners
Fat burners make your metabolism faster, so you can burn more fat and keep less of it. These diet supplements often use thermogenesis, which means the body makes heat. The hotter your inside temperature, the more your body uses and burns fat from food.
Thermogenesis works with lipolysis, a process where the body splits up fat. Lipolysis happens in the tissue and fat around the organs. Fat burners aim at any extra fat and change it into energy for the brain and body. For a list of the best weight loss supplements, look at Outlook.
● Carb Blockers
Carbohydrates are of two types: simple and complex. Carb blockers stop complex carbohydrates, which you can find in bread, pasta, and starchy foods. The drug stops the body from splitting up the carbs so that they don’t add to your calories.
Another good thing about carb blockers is their power to increase resistant starch levels in the intestines. The less carbohydrates you have for energy, the more starch stays in your gut. Resistant starch acts like dietary fiber, making people feel full for several hours.
● Appetite Suppressants
Appetite suppressants help people control their hunger and snacking. The weight loss pills reduce the number of hunger signals that go to the brain. Some appetite suppressants that need a doctor’s order are phentermine (Qsymia), naltrexone (Contrave), and liraglutide (Saxenda).
You can also find the best appetite suppressants in common foods and drinks, like green tea and coffee. The caffeine in these things lowers the want to eat for a short time. Caffeine can also boost fat-burning and energy.
"Do Diet Supplements Have Any Bad Effects? All medicines, including heat-producing weight loss pills, can have bad effects. These dangers change based on the amount, your health, and how much weight you want to lose. Some usual bad effects are:
Feeling dizzy
Feeling sick
Head pains
Stomach pains
Not regular poop
Hard poop
Feeling restless
Faster heart beat and blood pressure
Most of the bad effects are small and will go away after a few days. Other bad effects are more serious and can lead to addiction or misuse. If you have long-term bad effects, talk to a doctor for help.
Can Diet Supplements Help You Lose Fat Without Eating Well and Working Out? Diet supplements help you burn fat and lose weight, but they are not enough by themselves. A good diet and regular exercise are the best ways to remove extra body fat. Diet supplements are supposed to work with this plan.
You do not have to work out like an athlete or stop eating meat to lose weight. Try adding aerobic exercise to your routine three or four times a week. Some examples are biking, running, swimming, basketball, and pilates. Healthy meals should have a lot of fruits and vegetables, with few sweet snacks and highly processed carbs.
Can You Buy Diet Products Without a Doctor’s Order?
Yes, you can buy diet products without a doctor’s order, including phentermine-like pills. The problem is that they don’t have the best mix of active ingredients to lose weight the most. Other options, like PhenQ and PhenGold, offer more trustworthy ways to lose weight and have less bad effects. Unlike what many people think, the most popular diet products are actually found online.
"How Much Weight Can I Drop With Diet Pills?
There is no exact answer for how much weight you can lose. Your final body weight will depend mostly on how you look now. Someone who weighs 300 pounds can lose a lot more weight than someone who weighs 200 pounds.
Diet pill makers say that you should lose 5% of your weight in the first three months. Your percentage may be more or less depending on how much you weigh now. If you do not lose 5% of your weight in that time, your doctor may suggest a different medicine.
How Quick Does a Diet Supplement Work?
Weight loss does not happen right away. If you keep doing physical activity and eating well, you may see changes in the first two weeks. Remember that weight loss is a long-term goal, so it is important to make slow and lasting changes.
"Good Points
It has only natural, safe, plant-based, and approved ingredients It can help you lose weight and fat in many ways It does not have any illegal or harmful weight loss substances It has the right amount and mix of ingredients to work well and not cause problems It has very good feedback from both professional and normal users Bad Points
"Final Words
The Top Diet Supplements To Use Instead Of Doctor Weight Loss Drugs To Help You Lose Weight & Body Fat A doctor weight loss pill may help you lose weight and burn hard body fat fast, but many over-the-counter weight loss pills will do the same thing while being much safer. Our list of the top diet supplements should have a perfect option for everyone, but the top diet pill overall is Instant Knockout Cut.
It does everything by using the best amounts of tested ingredients and putting together the effects of hot fat burners, hunger reducers, and energy enhancers in a single diet pill. This will help you lose weight and burn fat normally, and make it easier to follow a healthy diet and exercise plan.
If, for any reason, you think that it is not the top diet pill for you, one of the other options on our list of the top diet supplements surely will be. For everyone else though, we strongly recommend that you try Instant Knockout Cut and see how well it can boost fat burning and weight loss for yourself.