England beat Pakistan by 52 runs in the second one-day international at Lord's on Saturday to take an unassailable 2-0 lead in a three-match series.
Pakistan, set 248 to win in a match reduced by rain to 47 overs per side, were dismissed for 195.
Lewis Gregory took 3-44 after making a valuable 40 in England's 247.
Phil Salt top-scored for England with 60 -- his maiden ODI fifty - and James Vince made 56, with Pakistan's Hasan Ali taking 5-51.
The series concludes with a day/nighter at Edgbaston on Tuesday.