Laxman was going great guns from one end after India lost opener Abhinav Mukund (62) and Virat Kohli (30) but his knock ended with a freak dismissal as he got himself stumped out after leaving a widish delivery from Shivnarine Chanderpaul.
Chanderpaul, who was bowling at this level for the first time since 2007, bowled an innocuous delivery outside the off stump. Laxman left that but his backfoot lost contact with the ground for a fraction of a second and an alert wicket-keeper Carlton Baugh did a smart job by taking off the bails in a jiffy.
Laxman shared a 84-run stand for the third wicket with Mukund and then added 52 for the next wicket with Kohli before going back to pavilion.
Mukund, Kohli and Laxman were all were guilty of poor judgment as the visitors are still 22 runs behind the West Indies score of 204 all out.
Mukund had serenely moved to his top Test score in his nascent career when he shaped to play a rising leg-spin from Bishoo towards midwicket but only edged it on to his pads and the lobbed chance was gratefully accepted by Adrian Barath at forward short leg.
Kohli seemed intent on making up for his lost chances of the series and had reached 30 without much ado when he poked at a harmless delivery from Darren Sammy down the leg-side and was brilliantly caught by Baugh.
All the three dismissed batsmen in the second session were completely settled as they threw away a golden opportunity to help themselves and their own team in splendid batting conditions.Mukund batted for 176 minutes and hit five fours from 149 balls while Laxman handled 129 balls in 207 minutes, caressing three boundaries.
Suresh Raina (9) and skipper Mahendra Singh Dhoni (4 ) were at the crease when the tea was taken.
Earlier, Mukund hit his maiden Test half-century to help India overcame early blows and reach a comfortable 102 for two at lunch.
The visitors were in complete control on a benign pitch and against an attack which operated without lead bowler Ravi Rampaul due to an upset stomach.
India, resuming at eight for no loss, lost Murali Vijay (5) and Rahul Dravid (5) in the opening session after adding just 10 runs to the overnight score.
Vijay was nearly bowled off a low full toss in Fidel Edwards' first over, squeezing the ball between the slip cordon for a four, but his tendency to push at the ball once again proved his undoing.
In Edwards' next over, a delivery took the edge of his bat on way to wicket-keeper Carlton Baugh's gloves.
The Tamil Nadu opener is in the middle of a wretched run of scores, the sequence of his five innings in the series reading 8,0,11,3 and 1.
Dravid then fell to Darren Sammy, making the normally passive West Indian captain roar in triumph as he hasn't done at any stage in this series.
Dravid played for an away movement at the delivery which kept coming straight and went between bat and pad to rattle the stumps.
Mukund and Laxman, the left-right combination, then gradually found their moorings as the hosts wilted under a hot son and a placid pitch.
There were not many fours hit but runs came at a fair clip as Indians looked to consolidate for a profitable day ahead.